Parathyroid hormone and fracture healing
2013 (English)In: Acta Orthopaedica, ISSN 1745-3674, E-ISSN 1745-3682, Vol. 84, no 1, 4-6 p.Article in journal (Refereed) Published
This annotation describes some early rat studies which conclude that parathyroid hormone (PTH) has more dramatic stimulatory effects on bone repair than on untraumatized bone. It also suggests, based on the effects of PTH on osteoblasts, that it is more likely to accelerate normal fracture healing than to prevent nonunion. The only 2 controlled clinical trials that have been published are critically discussed. Although both are encouraging and appear to show acceleration of normal fracture healing, they have methodological shortcomings that preclude definitive conclusions.
Place, publisher, year, edition, pages
Informa Healthcare, 2013. Vol. 84, no 1, 4-6 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-90079DOI: 10.3109/17453674.2013.771301ISI: 000314897500002OAI: oai:DiVA.org:liu-90079DiVA: diva2:612419