Hybrid Semiconducting Polymer Dot-Quantum Dot with Narrow-Band Emission, Near-Infrared Fluorescence, and High Brightness
2012 (English)In: Journal of the American Chemical Society, ISSN 0002-7863, E-ISSN 1520-5126, Vol. 134, no 17, 7309-7312 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
American Chemical Society (ACS), 2012. Vol. 134, no 17, 7309-7312 p.
IdentifiersURN: urn:nbn:se:liu:diva-90564DOI: 10.1021/ja3022973OAI: oai:DiVA.org:liu-90564DiVA: diva2:613833
This communication describes a new class of semiconducting polymer nanoparticle–quantum dot hybrid with high brightness, narrow emission, near-IR fluorescence, and excellent cellular targeting capability. Using this approach, we circumvented the current difficulty with obtaining narrow-band-emitting and near-IR-fluorescing semiconducting polymer nanoparticles while combining the advantages of both semiconducting polymer nanoparticles and quantum dots. We further demonstrated the use of this new class of hybrid nanomaterial for effective and specific cellular and subcellular labeling without any noticeable nonspecific binding. This hybrid nanomaterial is anticipated to find use in a variety of in vitro and in vivo biological applications.2013-04-022013-04-022013-04-10