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Effects of Trichloroethylene on the human vestibulo-oculomotor system
Linköping University. Department of Otolaryngology, University Hospital, Linköping, Sweden.
Linköping University. Department of Otolaryngology, University Hospital, Linköping, Sweden.
Linköping University. Department of Otolaryngology, University Hospital, Linköping, Sweden.
Linköping University. Department of Otolaryngology, University Hospital, Linköping, Sweden.
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1986 (English)In: Acta Oto-Laryngologica, ISSN 0001-6489, E-ISSN 1651-2251, Vol. 101, no 3-4, 193-199 p.Article in journal (Refereed) Published
Abstract [en]

Ten healthy volunteers were subjected to a vestibulo-oculomotor test battery before, during and 1 hour after trichloroethylene exposure. The concentration of trichloroethylene in in-spiratory air was 32–78 ppm (176429 mg/m3). The concentration of trichloroethylene in venous blood was followed throughout the experiment. The mean pulmonary uptake was estimated. Each test person was also subjected to a control experiment, breathing air free of trichloroethylene. A decreased ability to visually suppress the vestibulo-oculomotor reflex during sinusoidal stimulation was noticed during trichloroethylene exposure. One hour after exposure the test subjects showed a decreased maximum velocity of the voluntary saccade and a decreased ability to follow a sinusoidally moving target.

 

Place, publisher, year, edition, pages
Informa Healthcare, 1986. Vol. 101, no 3-4, 193-199 p.
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Medical and Health Sciences
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URN: urn:nbn:se:liu:diva-91758DOI: 10.3109/00016488609132827PubMedID: 3486543OAI: oai:DiVA.org:liu-91758DiVA: diva2:619020
Available from: 2013-05-01 Created: 2013-05-01 Last updated: 2017-12-06Bibliographically approved

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Larsby, BirgittaTham, RichardHydén, DagÖdkvist, Lars

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