Effects of Trichloroethylene on the human vestibulo-oculomotor system
1986 (English)In: Acta Oto-Laryngologica, ISSN 0001-6489, Vol. 101, no 3-4, 193-199 p.Article in journal (Refereed) Published
Ten healthy volunteers were subjected to a vestibulo-oculomotor test battery before, during and 1 hour after trichloroethylene exposure. The concentration of trichloroethylene in in-spiratory air was 32–78 ppm (176429 mg/m3). The concentration of trichloroethylene in venous blood was followed throughout the experiment. The mean pulmonary uptake was estimated. Each test person was also subjected to a control experiment, breathing air free of trichloroethylene. A decreased ability to visually suppress the vestibulo-oculomotor reflex during sinusoidal stimulation was noticed during trichloroethylene exposure. One hour after exposure the test subjects showed a decreased maximum velocity of the voluntary saccade and a decreased ability to follow a sinusoidally moving target.
Place, publisher, year, edition, pages
Informa Healthcare, 1986. Vol. 101, no 3-4, 193-199 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-91758DOI: 10.3109/00016488609132827PubMedID: 3486543OAI: oai:DiVA.org:liu-91758DiVA: diva2:619020