Integrated direct DNA/protein patterning and microfabrication by focused ion beam milling
2008 (English)In: Advanced Materials, ISSN 0935-9648, E-ISSN 1521-4095, Vol. 20, no 9, 1636-1643 p.Article in journal (Refereed) Published
Single and binary component patterning and integrated microfabrication of biomolecules, such as DNA and proteins, can be achieved by focused ion-beam (FIB) biolithography. Well-defined micropatterns are obtained by FIB milling on biomolecules immobilized on SiO2 wafers and protected by a thin Au film. The retention of biofunctionality is excellent (68–90%) and a feature size of down to 500 nm can be achieved for the patterns without significant loss of functionality.
Place, publisher, year, edition, pages
John Wiley & Sons, 2008. Vol. 20, no 9, 1636-1643 p.
biomolecules; patterning; focused ion beam; microfabrication; microdevices; DNA
IdentifiersURN: urn:nbn:se:liu:diva-92067DOI: 10.1002/adma.200701415OAI: oai:DiVA.org:liu-92067DiVA: diva2:620054