liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
Diagnostic procedures in autism spectrum disorders: a systematic literature review
Linköping University, Department of Medical and Health Sciences, Division of Community Medicine. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Local Health Care Services in Central Östergötland, Habilitation in Central County. Curtin University of Technology, Australia .
Curtin University of Technology, Australia .
Curtin University of Technology, Australia .
Curtin University of Technology, Australia .
2013 (English)In: European Child and Adolescent Psychiatry, ISSN 1018-8827, E-ISSN 1435-165X, Vol. 22, no 6, 329-340 p.Article, review/survey (Refereed) Published
Abstract [en]

At present, gold standard diagnosis of autism spectrum disorders (ASD) is a lengthy and time consuming process that requires suitably qualified multi-disciplinary team (MDT) personnel to assess behavioural, historical, and parent-report information to determine a diagnosis. A number of different tools have been developed to assist in determination. To optimise the diagnostic procedures, the best diagnostic instruments need to be identified. This study is a systematic review addressing the accuracy, reliability, validity and utility of reported diagnostic tools and assessments. To be included in this review, studies must have (1) identified an ASD diagnostic tool; (2) investigated either diagnostic procedure or the tools or personnel required; (3) be presented in English; (4) be conducted in the Western world; (5) be one of three types of studies [adapted from Samtani et al. in Cochrane Database Syst Rev 3:1-13, 2011], viz. (a) cohort studies or cross-sectional studies, (b) randomised studies of test accuracy, (c) case-control studies. MEDLINE, PsychINFO, Scopus, EMBASE, and Cochrane Library databases were scrutinised for relevant literature published from 2000 inclusive on 20th January 2012. In total, 68 articles were included. 17 tools were assessed. However, many lacked an evidence base of high quality-independent studies. The Autism Diagnostic Interview-Revised (ADI-R) and Autism Diagnostic Observation Schedule (ADOS) stood out with the largest evidence base and highest sensitivity and specificity. When the ADI-R and ADOS were used in combination they revealed levels of accuracy very similar to the correct classification rates for the current gold standard diagnostic procedure viz. 80.8 % for ASD. There is scope for future studies on the use of the ADI-R and ADOS in combination.

Place, publisher, year, edition, pages
Springer Verlag (Germany) , 2013. Vol. 22, no 6, 329-340 p.
Keyword [en]
Autism spectrum disorder, Diagnosis, Systematic review, ADOS, ADI-R
National Category
Engineering and Technology
URN: urn:nbn:se:liu:diva-95507DOI: 10.1007/s00787-013-0375-0ISI: 000319763200002OAI: diva2:635744

Funding Agencies|Disabilities Service Commission of Western Australia||

Available from: 2013-07-05 Created: 2013-07-05 Last updated: 2014-08-26

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Falkmer, Torbjorn
By organisation
Division of Community MedicineFaculty of Health SciencesHabilitation in Central County
In the same journal
European Child and Adolescent Psychiatry
Engineering and Technology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 73 hits
ReferencesLink to record
Permanent link

Direct link