liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
The efficacy of psychotherapy and pharmacotherapy in treating depressive and anxiety disorders: a meta-analysis of direct comparisons
Vrije University of Amsterdam, Netherlands Vrije University of Amsterdam, Netherlands Vrije University of Amsterdam Medical Centre, Netherlands Leuphana University, Germany .
Vrije University of Amsterdam, Netherlands Vrije University of Amsterdam, Netherlands Vrije University of Amsterdam Medical Centre, Netherlands .
Vrije University of Amsterdam, Netherlands Vrije University of Amsterdam, Netherlands Vrije University of Amsterdam Medical Centre, Netherlands .
Linköping University, Department of Behavioural Sciences and Learning, Psychology. Linköping University, Faculty of Arts and Sciences. Östergötlands Läns Landsting, Center of Paediatrics and Gynaecology and Obstetrics, Department of Gynaecology and Obstetrics in Linköping.ORCID iD: 0000-0003-4753-6745
Show others and affiliations
2013 (English)In: World Psychiatry, ISSN 1723-8617, E-ISSN 2051-5545, Vol. 12, no 2, 137-148 p.Article in journal (Refereed) Published
Abstract [en]

Although psychotherapy and antidepressant medication are efficacious in the treatment of depressive and anxiety disorders, it is not known whether they are equally efficacious for all types of disorders, and whether all types of psychotherapy and antidepressants are equally efficacious for each disorder. We conducted a meta-analysis of studies in which psychotherapy and antidepressant medication were directly compared in the treatment of depressive and anxiety disorders. Systematic searches in bibliographical databases resulted in 67 randomized trials, including 5,993 patients that met inclusion criteria, 40 studies focusing on depressive disorders and 27 focusing on anxiety disorders. The overall effect size indicating the difference between psychotherapy and pharmacotherapy after treatment in all disorders was g=0.02 (95% CI: -0.07 to 0.10), which was not statistically significant. Pharmacotherapy was significantly more efficacious than psychotherapy in dysthymia (g=0.30), and psychotherapy was significantly more efficacious than pharmacotherapy in obsessive-compulsive disorder (g=0.64). Furthermore, pharmacotherapy was significantly more efficacious than non-directive counseling (g=0.33), and psychotherapy was significantly more efficacious than pharmacotherapy with tricyclic antidepressants (g=0.21). These results remained significant when we controlled for other characteristics of the studies in multivariate meta-regression analysis, except for the differential effects in dysthymia, which were no longer statistically significant.

Place, publisher, year, edition, pages
WILEY-BLACKWELL , 2013. Vol. 12, no 2, 137-148 p.
Keyword [en]
Psychotherapy; antidepressant medication; depressive disorders; anxiety disorders; dysthymia; obsessive-compulsive disorder; meta-analysis
National Category
Social Sciences
Identifiers
URN: urn:nbn:se:liu:diva-96131DOI: 10.1002/wps.20038ISI: 000319883200017OAI: oai:DiVA.org:liu-96131DiVA: diva2:640755
Available from: 2013-08-14 Created: 2013-08-14 Last updated: 2017-12-06

Open Access in DiVA

No full text

Other links

Publisher's full text

Authority records BETA

Andersson, Gerhard

Search in DiVA

By author/editor
Andersson, Gerhard
By organisation
PsychologyFaculty of Arts and SciencesDepartment of Gynaecology and Obstetrics in Linköping
In the same journal
World Psychiatry
Social Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 257 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf