Surprising behavior of NXO-peptides toward the lithium hydroxide solvolysis
2013 (English)In: Tetrahedron Letters, ISSN 0040-4039, E-ISSN 1873-3581, Vol. 54, no 28, 3679-3682 p.Article in journal (Refereed) Published
An unexpected rearrangement of NXO peptides was observed during solvolysis of the methyl ester using lithium hydroxide as the base. It was found that the NXO-compounds rearranged into semioxamazide derivatives in which the ester is derived from the alcohol used as the reaction solvent.
Place, publisher, year, edition, pages
Elsevier , 2013. Vol. 54, no 28, 3679-3682 p.
Peptidomimetics, NXO-building blocks, L-Phenylalanine, Modified amino acids, Rearrangement
Engineering and Technology
IdentifiersURN: urn:nbn:se:liu:diva-95945DOI: 10.1016/j.tetlet.2013.05.010ISI: 000320689000026OAI: oai:DiVA.org:liu-95945DiVA: diva2:641757
Funding Agencies|Higher Education Commission (HEC) of Pakistan||2013-08-192013-08-122013-08-19