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Pregnancy and Birth Cohort Resources in Europe: a Large Opportunity for Aetiological Child Health Research
University of Copenhagen, Denmark .
University of Copenhagen, Denmark .
University of Newcastle, Australia .
University of Porto, Portugal .
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2013 (English)In: Paediatric and Perinatal Epidemiology, ISSN 0269-5022, E-ISSN 1365-3016, Vol. 27, no 4, 393-414 p.Article, review/survey (Refereed) Published
Abstract [en]

Background During the past 25 years, many pregnancy and birth cohorts have been established. Each cohort provides unique opportunities for examining associations of early-life exposures with child development and health. However, to fully exploit the large amount of available resources and to facilitate cross-cohort collaboration, it is necessary to have accessible information on each cohort and its individual characteristics. The aim of this work was to provide an overview of European pregnancy and birth cohorts registered in a freely accessible database located at Methods European pregnancy and birth cohorts initiated in 1980 or later with at least 300 mother-child pairs enrolled during pregnancy or at birth, and with postnatal data, were eligible for inclusion. Eligible cohorts were invited to provide information on the data and biological samples collected, as well as the timing of data collection. Results In total, 70 cohorts were identified. Of these, 56 fulfilled the inclusion criteria encompassing a total of more than 500000 live-born European children. The cohorts represented 19 countries with the majority of cohorts located in Northern and Western Europe. Some cohorts were general with multiple aims, whilst others focused on specific health or exposure-related research questions. Conclusion This work demonstrates a great potential for cross-cohort collaboration addressing important aspects of child health. The web site,, proved to be a useful tool for accessing information on European pregnancy and birth cohorts and their characteristics.

Place, publisher, year, edition, pages
Wiley-Blackwell , 2013. Vol. 27, no 4, 393-414 p.
Keyword [en]
European pregnancy birth cohort; cohort characteristics; cross-cohort collaboration
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-96461DOI: 10.1111/ppe.12060ISI: 000320474700011OAI: diva2:642931
Available from: 2013-08-23 Created: 2013-08-20 Last updated: 2013-08-23

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Ludvigsson, Johnny
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Division of Clinical SciencesFaculty of Health SciencesDepartment of Paediatrics in Linköping
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