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Long-term left ventricular support in patients with a mechanical aortic valve
Linköping University, Department of Medical and Health Sciences, Division of Cardiovascular Medicine. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Center, Department of Thoracic and Vascular Surgery.
Linköping University, Department of Medical and Health Sciences, Thoracic Surgery. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Center, Department of Thoracic and Vascular Surgery.
Linköping University, Department of Medical and Health Sciences, Cardiology. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Center, Department of Cardiology in Linköping.
Linköping University, Department of Medical and Health Sciences. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Center, Department of Thoracic and Vascular Surgery.
2013 (English)In: Scandinavian Cardiovascular Journal, ISSN 1401-7431, E-ISSN 1651-2006, Vol. 47, no 4, 236-239 p.Article in journal (Refereed) Published
Abstract [en]

Objectives. The presence of a mechanical prosthesis has been regarded as an increased risk of thromboembolic complications and as a relative contraindication for a left ventricular assist device (LVAD). Five patients in our center had a mechanical aortic valve at the time of device implantation and were studied regarding thromboembolic complications. Design. Five patients operated upon with an LVAD (1 HeartMate I (TM), 4 HeartMate II (TM)) between 2002 and 2011 had a mechanical aortic valve at the time of implantation. The first patient had a patch closure of the aortic valve. In four patients, the prosthesis was left in place. Anticoagulants included aspirin, warfarin, and clopidogrel. Results. The average and accumulated treatment times were 150 and 752 days, respectively. Three of the five patients showed early signs of valve thrombosis on echo with concomitant valve dysfunction. Four patients were transplanted without thromboembolic events during pump treatment. One patient died from a hemorrhagic stroke after 90 days on the LVAD. Conclusions. The strategy of leaving a mechanical heart valve in place at the time of LVAD implantation in five patients led to valvular thrombosis in three but did not provoke embolic events. It increased the complexity of postoperative anticoagulation.

Place, publisher, year, edition, pages
INFORMA HEALTHCARE, TELEPHONE HOUSE, 69-77 PAUL STREET, LONDON EC2A 4LQ, ENGLAND , 2013. Vol. 47, no 4, 236-239 p.
Keyword [en]
aortic valve, left ventricular support, mechanical valve
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-96976DOI: 10.3109/14017431.2013.795655ISI: 000322607700007OAI: oai:DiVA.org:liu-96976DiVA: diva2:645707
Available from: 2013-09-05 Created: 2013-09-02 Last updated: 2017-12-06

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Casimir Ahn, HenrikGranfeldt, HansHübbert, LailaPeterzén, Bengt

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Casimir Ahn, HenrikGranfeldt, HansHübbert, LailaPeterzén, Bengt
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Division of Cardiovascular MedicineFaculty of Health SciencesDepartment of Thoracic and Vascular SurgeryThoracic SurgeryCardiologyDepartment of Cardiology in LinköpingDepartment of Medical and Health Sciences
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