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High-throughput screening assays to evaluate the cardiotoxic potential of drugs
Linköping University, Department of Physics, Chemistry and Biology, Biotechnology. Linköping University, The Institute of Technology.
MultiChannel Systems GmbH, Reutlingen, Germany.
2013 (English)In: High-throughput screening methods in toxicity testing / [ed] Pablo Steinman, John Wiley & Sons, 2013, 403-420 p.Chapter in book (Other academic)
Abstract [en]

"High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe's REACH legislation and the US National Research Council"-- 

"This book describes the high-throughput in vitro methods available for toxicity testing, serving as a guide to scientists working in toxicity evaluation and risk assessment of chemicals and drugs"-- 

Place, publisher, year, edition, pages
John Wiley & Sons, 2013. 403-420 p.
Keyword [en]
cardiotoxicity, micro-electrode array, multi-electrode array, oxygen uptake, respiration measurement
National Category
Medical and Health Sciences Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)
Identifiers
URN: urn:nbn:se:liu:diva-97510ISBN: 978-1-118-06563-1 (print)ISBN: 978-1-29925-259-2 (print)OAI: oai:DiVA.org:liu-97510DiVA: diva2:652272
Available from: 2013-09-30 Created: 2013-09-13 Last updated: 2014-11-03Bibliographically approved

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Mandenius, Carl-Fredrik

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CiteExportLink to record
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Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
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Output format
  • html
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  • asciidoc
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