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Evidence-Based Point-of-Care Diagnostics: Current Status and Emerging Technologies
Chinese University of Hong Kong, Hong Kong, China .
Linköping University, Department of Physics, Chemistry and Biology, Biosensors and Bioelectronics. Linköping University, The Institute of Technology.ORCID iD: 0000-0003-3274-6029
Linköping University, Department of Clinical and Experimental Medicine, Division of Cell Biology. Linköping University, Faculty of Health Sciences.
Hong Kong University of Science and Technology, Hong Kong, China.
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2013 (English)In: Annual Review of Analytical Chemistry, ISSN 1936-1327 (Print), 1936-1335 (onlie), Vol. 6, 191-211 p.Article in journal (Refereed) Published
Abstract [en]

Point-of-care (POC) diagnostics brings tests nearer to the site of patient care. The turnaround time is short, and minimal manual interference enables quick clinical management decisions. Growth in POC diagnostics is being continuously fueled by the global burden of cardiovascular and infectious diseases. Early diagnosis and rapid initiation of treatment are crucial in the management of such patients. This review provides the rationale for the use of POC tests in acute coronary syndrome, heart failure, human immunodeficiency virus, and tuberculosis. We also consider emerging technologies that are based on advanced nanomaterials and microfluidics, improved assay sensitivity, miniaturization in device design, reduced costs, and high-throughput multiplex detection, all of which may shape the future development of POC diagnostics.

Place, publisher, year, edition, pages
Annual Reviews , 2013. Vol. 6, 191-211 p.
Keyword [en]
acute coronary syndrome, heart failure, human immunodeficiency virus, microfluidics, POC, tuberculosis
National Category
Engineering and Technology
URN: urn:nbn:se:liu:diva-98228DOI: 10.1146/annurev-anchem-062012-092641ISI: 000323887500010ISBN: 978-0-8243-4406-1OAI: diva2:653229

ISBN: 978-0-8243-4406-1

Available from: 2013-10-03 Created: 2013-10-03 Last updated: 2016-09-01Bibliographically approved

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Mak, Wing CheungCheung, Kwan Yee
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Biosensors and BioelectronicsThe Institute of TechnologyDivision of Cell BiologyFaculty of Health Sciences
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