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Comparison between Optical and MRI Trajectories in Stereotactic Neurosurgery
Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Instrumentation. (MINT)ORCID iD: 0000-0002-0012-7867
Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Instrumentation. (MINT)ORCID iD: 0000-0002-0555-8877
Linköping University, Department of Biomedical Engineering, Biomedical Instrumentation. Linköping University, The Institute of Technology. Institute for Medical and Analytical Technologies, University of Applied Sciences and Art Northwestern Switzerland, Basel. (MINT)
2014 (English)In: XIII Mediterranean Conference on Medical and Biological Engineering and Computing 2013 : MEDICON 2013, 25 - 28 September 2013, Seville, Spain / [ed] Laura M. Roa Romero, 2014, 49-51 p.Conference paper, Published paper (Refereed)
Abstract [en]

Deep brain stimulation (DBS) is an effective treatment for movement disorders e.g. Parkinson's disease. Thin electrodes are implanted into the deep brain structures by means of stereotactic technique and electrical stimulations are delivered to the brain tissue. Accuracy and safety during the implantation is important for optimal stimulation effect and minimization of bleedings. In addition to microelectrode recording and impedance measurements, intraoperative optical measurements using laser Doppler perfusion monitoring (LDPM) have previously been suggested as guidance tool during stereotactic DBS implantations. In this study we compare optical trajectories, recorded with LDPM ranging from cortex towards the subthalamic nucleus (STN), to the corresponding magnetic resonance imaging (MRI) trajectories. Inversed gray scales from the T2-weighted MRI were used for comparison with the total light intensity (TLI) representing tissue grayness. Both curves followed a general tendency with a deep dip in the vicinity to the left ventricle. MRI trajectories might help in predicting the optical trajectory but further studies including more data and fine tuning of the comparative methodology are required

Place, publisher, year, edition, pages
2014. 49-51 p.
Series
IFMBE Proceedings, ISSN 1680-0737 ; vol 41
Keyword [en]
Deep brain stimulation; Laser doppler perfusion monitoring; Magnetic resonance imaging; Stereotaxy
National Category
Other Medical Engineering
Identifiers
URN: urn:nbn:se:liu:diva-98652DOI: 10.1007/978-3-319-00846-2_12Scopus ID: 2-s2.0-84891330524ISBN: 9783319008455 (print)OAI: oai:DiVA.org:liu-98652DiVA: diva2:655184
Conference
XIII Mediterranean Conference on Medical and Biological Engineering and Computing
Available from: 2013-10-10 Created: 2013-10-10 Last updated: 2017-02-03Bibliographically approved

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Publisher's full textScopushttp://link.springer.com/chapter/10.1007%2F978-3-319-00846-2_12#

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Wårdell, KarinHaj-Hosseini, NedaHemm-Ode, Simone

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