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In vivo confocal microscopy of the cornea to assess tissue regenerative response after biomaterial implantation in humans.
Linköping University, Department of Clinical and Experimental Medicine, Ophthalmology. Linköping University, Faculty of Health Sciences.
Linköping University, Department of Clinical and Experimental Medicine, Regenerative Medicine. Linköping University, Faculty of Health Sciences.ORCID iD: 0000-0003-1222-6720
Linköping University, Department of Clinical and Experimental Medicine, Ophthalmology. Linköping University, Faculty of Health Sciences.
2013 (English)In: Corneal Regenerative Medicine: Methods and ProtocolsPart IV / [ed] Bernice Wright; Che J Connon, Humana Press, 2013, Vol. 1014, 211-23 p.Chapter in book (Other academic)
Abstract [en]

Laser-scanning in vivo confocal microscopy (IVCM) of the cornea is becoming an increasingly popular tool to examine the living human cornea with cellular-level detail in both healthy and pathologic states. Here, we describe the use of the IVCM technique to examine the processes of tissue healing and regeneration in the living human eye after biomaterial implantation. The regenerative response can be assessed by performing longitudinal IVCM imaging of a laboratory-made, cell-free biomaterial, after direct implantation into a pathologic eye as a primary alternative to human donor tissue transplantation.

Place, publisher, year, edition, pages
Humana Press, 2013. Vol. 1014, 211-23 p.
Series
Methods in Molecular Biology, ISSN 1064-3745 ; 1014
National Category
Cell and Molecular Biology
Identifiers
URN: urn:nbn:se:liu:diva-98695DOI: 10.1007/978-1-62703-432-6_15PubMedID: 23690016ISBN: 978-1-62703-431-9 (print)ISBN: 978-1-62703-432-6 (print)OAI: oai:DiVA.org:liu-98695DiVA: diva2:655381
Available from: 2013-10-11 Created: 2013-10-11 Last updated: 2015-11-18Bibliographically approved

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Lagali, NeilGriffith, MayFagerholm, Per

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CiteExportLink to record
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