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Ribonucleotides are not channeled into DNA in permeabilized mammalian cells
Karolinska institutet, Stockholm, Sweden.
Karolinska institutet, Stockholm, Sweden.
1983 (English)In: Biochemical and Biophysical Research Communications - BBRC, ISSN 0006-291X, E-ISSN 1090-2104, Vol. 115, no 3, 1022-1026 p.Article in journal (Refereed) Published
Abstract [en]

Reddy and Pardee earlier reported that permeabilized CHEF/18 cells (J. Biol. Chem 257, 12526) or soluble extracts from such cells (Cell 32, 443) under the proper conditions preferentially incorporated a labeled ribonucleotide (CDP) into DNA without dilution by an excess of non-labeled dCTP, suggesting channeling of ribonucleotides into DNA by a multiprotein complex. Here we present results suggesting that in these experiments CDP was incorporated into RNA and not into DNA.

Place, publisher, year, edition, pages
Elsevier, 1983. Vol. 115, no 3, 1022-1026 p.
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Medical and Health Sciences
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URN: urn:nbn:se:liu:diva-98741PubMedID: 6684923OAI: oai:DiVA.org:liu-98741DiVA: diva2:655837
Available from: 2013-10-14 Created: 2013-10-14 Last updated: 2017-12-06Bibliographically approved

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Spyrou, Giannis

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