liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Frailty is independently associated with 1-year mortality for elderly patients with non-ST-segment elevation myocardial infarction
Linköping University, Department of Medical and Health Sciences, Division of Health Care Analysis. Linköping University, Faculty of Health Sciences.
Linköping University, Department of Medical and Health Sciences, Division of Cardiovascular Medicine. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Center, Department of Cardiology in Linköping.ORCID iD: 0000-0002-2608-2062
Linköping University, Department of Medical and Health Sciences, Division of Cardiovascular Medicine. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Center, Department of Cardiology in Linköping.ORCID iD: 0000-0002-9375-5087
Linköping University, Department of Medical and Health Sciences, Division of Cardiovascular Medicine. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Center, Department of Cardiology in Linköping.
Show others and affiliations
2014 (English)In: European Journal of Preventive Cardiology, ISSN 2047-4873, E-ISSN 2047-4881, Vol. 21, no 10, 1216-1224 p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: For the large population of elderly patients with cardiovascular disease, it is crucial to identify clinically relevant measures of biological age and their contribution to risk. Frailty is denoting decreased physiological reserves and increased vulnerability. We analysed the manner in which the variable frailty is associated with 1-year outcomes for elderly non-ST-segment elevation myocardial infarction (NSTEMI) patients. METHODS AND RESULTS: Patients aged 75 years or older, with diagnosed NSTEMI were included at three centres, and clinical data including judgment of frailty were collected prospectively. Frailty was defined according to the Canadian Study of Health and Aging Clinical Frailty Scale. Of 307 patients, 149 (48.5%) were considered frail. By Cox regression analyses, frailty was found to be independently associated with 1-year mortality after adjusting for cardiovascular risk and comorbid conditions (hazard ratio 4.3, 95% CI 2.4-7.8). The time to the first event was significantly shorter for frail patients than for nonfrail (34 days, 95% CI 10-58, p = 0.005). CONCLUSIONS: Frailty is strongly and independently associated with 1-year mortality. The combined use of frailty and comorbidity may constitute an important risk prediction concept in regard to cardiovascular patients with complex needs.

Place, publisher, year, edition, pages
Sage Publications, 2014. Vol. 21, no 10, 1216-1224 p.
Keyword [en]
Elderly, frailty, mortality, myocardial infarction
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:liu:diva-99008DOI: 10.1177/2047487313490257ISI: 000342818000003PubMedID: 23644488OAI: oai:DiVA.org:liu-99008DiVA: diva2:656265
Available from: 2013-10-15 Created: 2013-10-15 Last updated: 2017-12-06

Open Access in DiVA

fulltext(482 kB)246 downloads
File information
File name FULLTEXT01.pdfFile size 482 kBChecksum SHA-512
cacb3412a811c23795b464415beecc8cc2f02875b37c5c81e14a563fa5a26418cb24d3912e1418a4e0776a728009119bbd0e02e636c9e036898ea113d2d698bf
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Authority records BETA

Ekerstad, NiklasSwahn, EvaJanzon, MagnusAlfredsson, JoakimLindenberger, MarcusAndersson, DavidCarlsson, Per

Search in DiVA

By author/editor
Ekerstad, NiklasSwahn, EvaJanzon, MagnusAlfredsson, JoakimLindenberger, MarcusAndersson, DavidCarlsson, Per
By organisation
Division of Health Care AnalysisFaculty of Health SciencesDivision of Cardiovascular MedicineDepartment of Cardiology in LinköpingEconomicsFaculty of Arts and Sciences
In the same journal
European Journal of Preventive Cardiology
Clinical Medicine

Search outside of DiVA

GoogleGoogle Scholar
Total: 246 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 365 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf