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Diabetes-induced decrease in renal oxygen tension: effects of an altered metabolism
Uppsala universitet, Institutionen för medicinsk cellbiologi.
Uppsala universitet, Institutionen för medicinsk cellbiologi.
Uppsala universitet, Institutionen för medicinsk cellbiologi.
Uppsala universitet, Institutionen för medicinsk cellbiologi.
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2006 (English)In: Advances in Experimental Medicine and Biology, ISSN 0065-2598, E-ISSN 2214-8019, Vol. 578, 161-166 p.Article in journal (Refereed) Published
Abstract [en]

During conditions with experimental diabetes mellitus, it is evident that several alterations in renal oxygen metabolism occur, including increased mitochondrial respiration and increased lactate accumulation in the renal tissue. Consequently, these alterations will contribute to decrease the interstitial pO2, preferentially in the renal medulla of animals with sustained long-term hyperglycemia.

Place, publisher, year, edition, pages
2006. Vol. 578, 161-166 p.
Keyword [en]
Animals, Diabetes Mellitus; Experimental/metabolism/physiopathology, Diabetic Nephropathies/*metabolism/*physiopathology, Humans, Kidney/*metabolism/physiology, Oxygen Consumption/physiology
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Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-99289PubMedID: 16927687OAI: oai:DiVA.org:liu-99289DiVA: diva2:657244
Available from: 2008-01-21 Created: 2013-10-15 Last updated: 2017-12-06

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Palm, FredrikCarlsson, Per-OlaFasching, AngelicaHansell, PeterLiss, Per

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