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Intravoxel Incoherent Motion MR Imaging of the Kidney: Pilot Study
Uppsala universitet, Enheten för radiologi.
Uppsala universitet, Integrativ Fysiologi.
Uppsala universitet, Enheten för radiologi.
Uppsala universitet, Integrativ Fysiologi.
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2013 (English)In: Advances in Experimental Medicine and Biology, ISSN 0065-2598, E-ISSN 2214-8019, Vol. 765, 55-58 p.Article in journal (Refereed) Published
Abstract [en]

MR examinations (Achieva 3 T, Philips, Best, The Netherlands) were performed at five different occasions in a healthy volunteer (male 60 years) and in one renal cancer patient (male 78 years) with normal renal function (creatinine 88 μmol/L). Intravoxel incoherent motion (IVIM) coefficients D + D* were measured using respiratory-triggered diffusion-weighted spin-echo echo-planar imaging. Perfusion data of the patient were acquired using a saturation-recovery gradient-echo sequence and with the bolus of Gd-BOPTA (Multihance). D + D* were computed by monoexponential fitting of MR signal intensity attenuation versus b for b = 0, 50, 100, 150 s/mm2. Perfusion parameters were evaluated with “NordicICE” software. The map of D + D* was compared qualitatively with the perfusion map computed from the Gd scan. D + D* values of the cortex and medulla were in the range 2.3–2.7 and 1.1–1.6 × 10-3 mm2/s, respectively. In conclusion, in this pilot study a good qualitative relation between IVIM variables D + D* and renal perfusion has been found.

Place, publisher, year, edition, pages
2013. Vol. 765, 55-58 p.
National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:liu:diva-99618DOI: 10.1007/978-1-4614-4989-8_8PubMedID: 22879014OAI: oai:DiVA.org:liu-99618DiVA: diva2:657392
Available from: 2012-10-09 Created: 2013-10-18 Last updated: 2017-12-06

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Eckerbom, PerHansell, PeterBjerner, TomasPalm, FredrikWeis, JanLiss, Per

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