Medullary thyroid carcinoma - Characteristics, diagnostics, therapy and follow-up [Medulläres Schilddrüsenkarzinom - Besonderheiten, Diagnostik, Therapie und Nachsorge]
2012 (English)In: Klinikarzt, ISSN 0341-2350, Vol. 41, no 10, 476-480 p.Article in journal (Refereed) Published
Medullary thyroid carcinoma (MTC) is a rare malignant tumor of the thyroid gland, it probably accounts for about 3 - 8% of all thyroids cancers. In contrast to the majority of thyroid cancers that develop from thyreocytes, MTC has its origins in parafollicular C cells. Among others, these cells synthesize calcitonin which thus represents a very sensitive tumor marker. MTC is not responsive to the usually employed conventional radio-iodine therapy because C cells, in contrast to threocytes, do not take up iodine. This fact places additional demands on surgical treatment. The management of MTCs that are not suitable for operative treatment because of their inoperable nature or, respectively, due to the presence of distant disseminated metastases is a hot topic of current intensive research. © Georg Thieme Verlag KG · Stuttgart · New York.
Place, publisher, year, edition, pages
Georg Thieme Verlag , 2012. Vol. 41, no 10, 476-480 p.
C cells; follow-up; medullary; therapy; Thyroid cancer
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-100943DOI: 10.1055/s-0032-1330949OAI: oai:DiVA.org:liu-100943DiVA: diva2:664512