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Sound-induced differential motion within the hearing organ
Karolinska Institutet, Stockholm, Sweden.
Karolinska Institutet, Stockholm, Sweden.
2003 (English)In: Nature Neuroscience, ISSN 1097-6256, E-ISSN 1546-1726, Vol. 6, no 5, 446-448 p.Article in journal (Refereed) Published
Abstract [en]

Hearing depends on the transformation of sound-induced basilar membrane vibration into deflection of stereocilia1 on the sensory hair cells, but the nature of these mechanical transformations is unclear. Using new techniques to visualize and measure sound-induced vibration deep inside the moving organ of Corti, we found that two functionally crucial structures, the basilar membrane and the reticular lamina, have different centers of rotation, leading to shearing motion and rapid deformation for the mechanoreceptive outer hair cells. Structural relations within the organ of Corti are much more dynamic than previously thought, which clarifies how outer hair cell molecular motors can have such a powerful effect.

Place, publisher, year, edition, pages
Nature Publishing Group, 2003. Vol. 6, no 5, 446-448 p.
National Category
Neurosciences
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URN: urn:nbn:se:liu:diva-101074DOI: 10.1038/nn1047PubMedID: 12692558OAI: oai:DiVA.org:liu-101074DiVA: diva2:665142
Available from: 2013-11-19 Created: 2013-11-19 Last updated: 2017-12-06Bibliographically approved

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Fridberger, Anders

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