Quantification of Stenotic Flow Using Spiral 3D Phase-Contrast MRI
2013 (English)Manuscript (preprint) (Other academic)
Purpose: To evaluate the feasibility of spiral 3D phase contrast MRI for the assessment of velocity, volume flow rate, peak velocity and turbulent kinetic energy in stenotic flow.
Materials and Methods: A-stack-of-spirals 3D phase contrast MRI sequence was evaluated in-vitro against a conventional Cartesian sequence. Measurements were made in a flow phantom with a 75% stenosis. Both spiral and Cartesian imaging were performed using different scan orientations and flow rates. Volume flow rate, peak velocity and turbulent kinetic energy (TKE) were computed for both methods. For further validation, the estimated TKE was compared to computational fluid dynamics (CFD) data.
Results: The volume flow rate, peak velocity and TKE obtained with spiral 4D flow MRI agreed well with Cartesian data and CFD data. As expected, the short echo time of the spiral sequence resulted in less prominent displacement artifacts compared to the Cartesian sequence. However, both spiral and Cartesian flow rate estimates were sensitive to displacement when the flow was oblique to the encoding directions.
Conclusion: Spiral 3D phase contrast MRI appears favorable for the assessment of stenotic flow. The spiral sequence was more than three times faster and less sensitive to displacement artifacts when compared to a conventional Cartesian sequence.
Place, publisher, year, edition, pages
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-101107OAI: oai:DiVA.org:liu-101107DiVA: diva2:665280