A pentameric luminescent-conjugated oligothiophene for optical imaging of in vitro-formed amyloid fibrils and protein aggregates in tissue sections.
2012 (English)In: Methods in molecular biology (Clifton, N.J.), ISSN 1940-6029, Vol. 849, 425-434 p.Article in journal (Refereed) Published
Luminescent-conjugated oligo- and polythiophenes (LCOs and LCPs) are valuable tools for optical imaging of a plethora of protein aggregates associated with amyloidoses. Here, we describe the utilization of an anionic pentameric LCO, p-FTAA, for staining of protein aggregates in a variety of platforms, including in vitro-formed amyloid fibrils and tissue sections.
Place, publisher, year, edition, pages
Humana Press , 2012. Vol. 849, 425-434 p.
IdentifiersURN: urn:nbn:se:liu:diva-101130DOI: 10.1007/978-1-61779-551-0_29OAI: oai:DiVA.org:liu-101130DiVA: diva2:665568