Dressing the split-thickness skin graft donor site: a randomized clinical trial
2014 (English)In: Advances in Skin & Wound Care, ISSN 1527-7941, E-ISSN 1538-8654, Vol. 27, no 1, 20-25 p.Article in journal (Refereed) Published
OBJECTIVE: The primary objective of this study was to compareAquacel (ConvaTec, Skillman, New Jersey), Allevyn (Smith &Nephew, St Petersburg, Florida), and Mediskin I (Mo¨ lnlycke, HealthCare AB, Gothenburg, Sweden) in the treatment of split-thicknessskin graft donor sites.
DESIGN: This study was performed as a prospective randomized,3-arm, clinical study.
SETTING: A clinical study performed at a hand and plastic surgerydepartment with burn unit.
PARTICIPANTS: The study included 67 adults with a total of73 donor sites, which were on the thigh, not reharvested, andranged between 30- and 400-cm2 area.
INTERVENTIONS: Subjects were randomly assigned to treatmentwith Aquacel, Allevyn, or Mediskin I.
MAIN OUTCOME MEASURES: The donor site was assessed onpostoperative days 3, 14, and 21 for healing, infection, pain,impact on everyday life, ease of use, and cost.
MAIN RESULTS: The obtained results demonstrate significantlyfaster re-epithelialization for patients treated with Aquacel orMediskin I compared with Allevyn. Regarding infections, therewere no significant differences between the groups. Patientswearing Aquacel experienced significantly less pain changing thedressing and less impact on everyday life than the patientswearing Allevyn. Aquacel was shown to be significantly easier forthe caregiver to use than Allevyn and Mediskin I. There is asignificant difference in cost of treatment between the dressings,whereas Mediskin I is the most expensive.
CONCLUSION: The authors’ results support the use of Aquacel in thetreatment of split-thickness skin graft donor sites. Aquacel has alow cost per unit, is user friendly, gives short healing time, andminimizes patient discomfort.
Place, publisher, year, edition, pages
Lippincott Williams & Wilkins, 2014. Vol. 27, no 1, 20-25 p.
split-thickness skin grafting, donor sites, wound dressing
Other Clinical Medicine
IdentifiersURN: urn:nbn:se:liu:diva-103995DOI: 10.1097/01.ASW.0000437786.92529.22ISI: 000335388100005PubMedID: 24343389OAI: oai:DiVA.org:liu-103995DiVA: diva2:693789