Structuring of nanoelectrode array of Au nanoparticle on two-dimensional WS2 interface for electrochemical biosensing
2014 (English)In: 24th Anniversary World Congress on Biosensors – Biosensors 2014, Elsevier, 2014Conference paper, Poster (Other academic)
The reduction in size of an electrode improves the mass transport of molecules to the electrode surface because of the contribution of radial diffusion. Thus, nanoelectrodes are particularly well suited for electroanalytical applications . However, the construction of nanoelectrodes generally involve specialised equipment that is relatively complex to fabricate and not suitable for mass production. However nanostructuring of macroelectrode surface by metallic nanoparticles have been recently used in a variety of biosensing applications due to their enhanced surface area, precise biomolecule-electrode connections. For electrochemical sensing, conductive nanostructures immobilised on electrodes enhance electrocatalytic behaviour due the quantum confinement and exhibit unique features including favourable Faradic-to-capacitive current ratios, higher current densities and faster mass transport by convergent diffusion than their larger micro/macro electrode counterparts. In order to increase biosensor current output to measurable levels, large arrays of nanostructures have been immobilised on electrode surface . The nanoelectrode arrays biosensors have been fabricated by various nanostructures such as nanowires, nanotubes and nanoparticles, have demonstrated promising results, displaying high sensitivity and fast response time.
In this study, we present a new nanostructured biosensor to address many limitations that nanoelectrode array biosensors currently face. Here, we used WS2-Au nanoparticle self-assembled structures as an interface element for electrochemical sensing of H2O2. The combination of zero-dimension nanoparticles on a two-dimensional support that is arrayed in the third dimension creates a biosensor platform with exceptional characteristics. The versatility of the biosensor platform was demonstrated by altering biosensor performance with a sensitivity (11.64 µA/µM/cm2), detection limit (0.085 µM), and linear sensing range (0.05-12.0 mM). This promising approach provides a novel methodology for structuring of Au nanoarray on two-dimensional surface and furnishes the basis for fabrication of flexible ultra-sensitive and efficient electrochemical biosensors.
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IdentifiersURN: urn:nbn:se:liu:diva-108430OAI: oai:DiVA.org:liu-108430DiVA: diva2:730296
24th Anniversary World Congress on Biosensors – Biosensors 2014, 27-30 May 2014, Melbourne, Australia
FunderSwedish Research Council