Automatic and Quantitative Assessment of Total and Regional Muscle Tissue Volume using Multi-Atlas Segmentation
2014 (English)Conference paper, Poster (Other academic)
Accurate and precise assessment of human muscle tissue is important for further understanding of different muscle diseases and syndromes. We present a rapid whole body MR method for automatic quantification of total and regional muscle volume. The method is based on multi-atlas segmentation of intensity corrected water-fat separated images. The method was validated with a leave-one-out approach, using manually segmented atlases from 10 subjects as ground truth. The result gave a coefficient of variation on total muscle volume equal to 1.25±1.35 % (mean ± standard deviation). The method enables cost-efficient large-scale studies, investigating conditions such as sarcopenia and muscular dystrophies.
Place, publisher, year, edition, pages
Radiology, Nuclear Medicine and Medical Imaging Medical Image Processing
IdentifiersURN: urn:nbn:se:liu:diva-109034OAI: oai:DiVA.org:liu-109034DiVA: diva2:735713
ISMRM 22nd Annual Meeting & Exhibition, 10 -16 May, 2014, Milan, Italy