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An elevated ratio of early to late diastolic filling velocity recovers after heart transplantation in a time-dependent manner
University of Tokyo, Japan .
University of Tokyo, Japan .
University of Tokyo, Japan .
University of Tokyo, Japan .
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2012 (English)In: Journal of Cardiology, ISSN 0914-5087, E-ISSN 1876-4738, Vol. 60, no 4, 295-300 p.Article in journal (Refereed) Published
Abstract [en]

Background

Several groups have reported that an elevated ratio of early (E) to late (A) diastolic filling velocities is observed in patients after heart transplantation. However, the mechanism has not been fully analyzed.

Methods

Serial echocardiography and hemodynamic study were performed in 16 patients who had received heart transplantation and had no evidence of rejection during 1 month after the operation.

Results

On Day 1 after the surgery, E/A ratio was higher and peak velocity of A wave was lower than normal range among the patients after heart transplantation. E/A ratio and peak velocity of A wave gradually normalized during 1 moth after the surgery. Meanwhile, early mitral annular velocity and pulmonary capillary wedge pressure remained within normal range during the study period.

Conclusions

Longer ischemic time during heart transplantation procedure may cause atrial stunning, but it appears to recover within 1 month. We have to be alert to misinterpretation of this “psuedo-psuedonormal” mitral inflow pattern early after transplantation.

Place, publisher, year, edition, pages
Elsevier, 2012. Vol. 60, no 4, 295-300 p.
Keyword [en]
Diastolic dysfunction; Echocardiography; Left atrium; Surgery
National Category
Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-111194DOI: 10.1016/j.jjcc.2012.05.011ISI: 000310107500023PubMedID: 22727438OAI: oai:DiVA.org:liu-111194DiVA: diva2:754480
Note

Funding Agencies|FUGAKU trust for medicinal research; Japan Society for the Promotion of Science [224943]; Japan Society for the Promotion of Science (JSPS)

Available from: 2014-10-10 Created: 2014-10-10 Last updated: 2017-12-05Bibliographically approved

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Kato, Naoko

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CiteExportLink to record
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Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf