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Five-region study finds no evidence of undiagnosed type 2 diabetes in Swedish 11- to 13-year-olds
Umeå University, Sweden.
Umeå University, Sweden.
Lund University, Sweden.
Linköping University, Department of Clinical and Experimental Medicine, Division of Clinical Sciences. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Center of Paediatrics and Gynaecology and Obstetrics, Department of Paediatrics in Norrköping.
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2014 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 103, no 10, 1078-1082 p.Article in journal (Refereed) Published
Abstract [en]

AimChildhood obesity is now an established public health problem in most developed countries, and there is concern about a parallel increase of type 2 diabetes. The aim of this study was to estimate the prevalence of undiagnosed type 2 diabetes in overweight Swedish school children from 11 to 13years of age. MethodsBody mass index (BMI) was measured in 5528 schoolchildren in the 6th grade, from 11 to 13years of age, in five different regions in Sweden. Overweight was defined by international age- and sex-specific BMI cut-offs, corresponding to adult BMI cut-offs of 25kg/m(2) at 18years of age (ISO-BMI 25, n=1275). Haemoglobin A1c (HbA1c) was measured in 1126 children with ISO-BMI 25. Children with a Diabetes Control and Complications Trial aligned HbA1c 6.1% on two occasions underwent an oral glucose tolerance test (OGTT) to establish the diabetes diagnosis. ResultsOf 1126 children with ISO-BMI 25, 24 (2.1%) had at least one HbA1c value 6.1%. Three of them had HbA1c 6.1% on two occasions, and all of them had a normal OGTT. ConclusionIn this cross-sectional, population-based screening study of a high-risk group of 11- to 13-year-old Swedish school children, we found no indication of undiagnosed diabetes or impaired glucose tolerance.

Place, publisher, year, edition, pages
Wiley , 2014. Vol. 103, no 10, 1078-1082 p.
Keyword [en]
Childhood obesity; Diabetes mellitus type 2; Epidemiology
National Category
Clinical Medicine
URN: urn:nbn:se:liu:diva-112040DOI: 10.1111/apa.12729ISI: 000342753400022PubMedID: 24976437OAI: diva2:763898

Funding Agencies|FAS; Swedish Council for Working Life and Social Research; Swedish Research Council

Available from: 2014-11-17 Created: 2014-11-13 Last updated: 2015-03-30

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Högberg, Lotta
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Division of Clinical SciencesFaculty of Health SciencesDepartment of Paediatrics in Norrköping
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