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Regional variation in prevalence and healthcare utilization due to epilepsy in Sweden
University of Gothenburg, Sweden; University of Gothenburg, Sweden.
UCB Pharma, Denmark.
Linköping University, Department of Clinical and Experimental Medicine, Division of Neuroscience. Linköping University, Faculty of Health Sciences. Linköping University, Center for Medical Image Science and Visualization (CMIV). Östergötlands Läns Landsting, Local Health Care Services in Central Östergötland, Department of Neurology. Östergötlands Läns Landsting, Local Health Care Services in West Östergötland, Department of Medical Specialist in Motala.
2014 (English)In: Acta Neurologica Scandinavica, ISSN 0001-6314, E-ISSN 1600-0404, Vol. 130, no 6, 354-359 p.Article in journal (Refereed) Published
Abstract [en]

ObjectiveTo estimate the regional differences in the prevalence of epilepsy and the associated costs due to inpatient and outpatient care and anti-epileptic drug (AED) utilization for the years 2005 and 2011 in Sweden. MethodsRegion-specific estimates of the prevalence of epilepsy were obtained using a method based on a linkage of the healthcare and pharmaceutical registries and the cause of death registry. Regional cost components were estimated using registry data by region on inpatient and outpatient care utilization, AED sales, and mortality. Per-patient utilization and monetary costs were calculated. ResultsEstimated prevalence of epilepsy varied substantially across the regions in 2011, from 0.76% in Jamtland to 1.08% in Gotland. The national prevalence was 0.88%. The average number of hospitalizations per patient and year decreased at the national level between 2005 and 2011. At the national level, the per-patient specialized care (outpatient) utilization also decreased between 2005 and 2011. However, at the regional level, the decrease was not uniform, and in some counties, the per-patient utilization increased during the period studied. The per-patient utilization of AEDs increased in all counties, except Kronoberg, between 2005 and 2011. Moreover, between-region differences in healthcare and AED utilization, and significant differences between regions and national averages were revealed. Similarly, regional per-patient costs were shown to deviate from the national average in 13 of 21 regions. ConclusionsThere is significant variation in the prevalence of epilepsy and the provision of health care for patients with epilepsy across the different regions of Sweden.

Place, publisher, year, edition, pages
Wiley: 12 months , 2014. Vol. 130, no 6, 354-359 p.
Keyword [en]
epilepsy; anti-epileptic drugs; anti-epileptic drug utilization; regional epilepsy prevalence
National Category
Clinical Medicine
URN: urn:nbn:se:liu:diva-112603DOI: 10.1111/ane.12274ISI: 000344242800002PubMedID: 25040145OAI: diva2:770223

Funding Agencies|UCB Nordic, Denmark

Available from: 2014-12-10 Created: 2014-12-05 Last updated: 2015-04-15

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Landtblom, Anne-Marie
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Division of NeuroscienceFaculty of Health SciencesCenter for Medical Image Science and Visualization (CMIV)Department of NeurologyDepartment of Medical Specialist in Motala
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Acta Neurologica Scandinavica
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