Potentiometric creatinine biosensor based on ZnO nanowires
2012 (English)In: Journal of Nanoscience Letters, ISSN 2231-4008 (print), 2231-4016 (online), Vol. 2, no 4, 24-24 p.Article in journal (Refereed) Published
In the present work, we have grown well-aligned zinc oxide (ZnO) nanowires (NWs) on the surface of gold coated glass substrates by a low temperature aqueous chemical growth (ACG) approach and utilized it as a potentiometric creatinine biosensor. This was achieved by electrostatic immobilization of creatinine deiminase (CD) on the surface of the ZnO NWs followed by applying a chitosan membrane in conjunction with glutaraldehyde. This immobilization resulted in a sensitive, selective, stable, reproducible and fast creatinine biosensor. The potentiometric response of the ZnO sensor vs. Ag/AgCl reference electrode was found to be linear over a wide logarithmic concentration of creatinine electrolyte solution ranging from 1-1000 µM. The sensor illustrates good linear sensitivity slope curve of ~33.9 mV/decade along with a rapid response time of ~7 s. Furthermore, the sensor response was unaffected by normal concentrations of common interferences such as potassium, calcium, magnesium, sodium, copper ions and glucose.
Place, publisher, year, edition, pages
Cognizure , 2012. Vol. 2, no 4, 24-24 p.
ZnO nanowires; Potentiometric nanosensor; Electrochemical nanodevices; Creatinine deiminase; Creatinine
Electrical Engineering, Electronic Engineering, Information Engineering
IdentifiersURN: urn:nbn:se:liu:diva-112909OAI: oai:DiVA.org:liu-112909DiVA: diva2:773672