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Middle cerebral artery circulation during carotid surgery. A transcranial Doppler study.
Linköping University, Department of Medical and Health Sciences, Clinical Physiology. Linköping University, Faculty of Health Sciences. Linköping University, Center for Medical Image Science and Visualization (CMIV). Östergötlands Läns Landsting, Heart and Medicine Center, Department of Clinical Physiology in Linköping.
(Sahlgrenska University Hospital, Göteborg)
(Sahlgrenska University Hospital, Göteborg)
(Sahlgrenska University Hospital, Göteborg)
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2000 (English)In: Scandinavian Cardiovascular Journal, ISSN 1401-7431, Vol. 34, no 6, 597-602 p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: Perioperative carotid cross-clamping might induce low stump pressures as well as hypoperfusion of the middle cerebral artery. In this study blood flow velocities in the middle cerebral artery were compared with intraoperative measurements of the poststenotic carotid blood pressure.

DESIGN: Forty-one patients with internal carotid artery stenosis were operated on without shunting, under general anesthesia. Poststenotic carotid pressures and middle cerebral artery flow velocities were measured before and during cross-clamping. The hemodynamic responses to preoperative carotid compressions and intraoperative cross-clamping were evaluated.

RESULTS: In seven patients the poststenotic carotid blood pressure decreased on clamping despite unchanged or even increased middle cerebral artery blood flow velocities. In all other patients, pressure changes were significantly correlated to the decrease in middle cerebral artery blood flow velocities. Autoregulatory blood flow velocity responses after preoperative common carotid artery compression were not reproducible by cross-clamping.

CONCLUSIONS: Stump blood pressure measurements may not reflect middle cerebral artery perfusion in about 20% of thrombendarterectomies performed under general anesthesia. A possible explanation might be dimished cerebral autoregulation and changes in collateral flow distributions.

Place, publisher, year, edition, pages
2000. Vol. 34, no 6, 597-602 p.
National Category
Clinical Medicine
URN: urn:nbn:se:liu:diva-113411PubMedID: 11214015OAI: diva2:781769
Available from: 2015-01-19 Created: 2015-01-19 Last updated: 2015-01-26

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Zachrisson, Helene
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Clinical PhysiologyFaculty of Health SciencesCenter for Medical Image Science and Visualization (CMIV)Department of Clinical Physiology in Linköping
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Scandinavian Cardiovascular Journal
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