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Globalization, climate change, and transgenerational epigenetic inheritance: will our descendants be at risk?
Linköping University, Department of Physics, Chemistry and Biology, Biology. Linköping University, The Institute of Technology.
Linköping University, Department of Physics, Chemistry and Biology, Biology. Linköping University, The Institute of Technology. (Etologi)
2015 (English)In: Clinical Epigenetics, E-ISSN 1868-7083, Vol. 7, no 8Article in journal, Letter (Refereed) Published
Abstract [en]

Transgenerational epigenetic inheritance has gained increased attention due to the possibility that exposure to environmental contaminants induce diseases that propagate  across generations through epigenomic alterations in gametes. In laboratory animals,exposure to environmental toxicants such as fungicides, pesticides, or plastic compounds has been shown to produce abnormal reproductive or metabolic phenotypes that are transgenerationally transmitted. Human exposures to environmental toxicants have increased due to industrialization and globalization, as well as the incidence of diseases shown to be transgenerationally transmitted in animal models. This new knowledge poses an urgent call to study transgenerational  consequences of current human exposures to environmental toxicants.

Place, publisher, year, edition, pages
BioMed Central, 2015. Vol. 7, no 8
Keyword [en]
Transgenerational epigenetic inheritance, Environmental exposures, Non-infectious diseases, Globalization, intustrialization, Food industry
National Category
Biological Sciences
Identifiers
URN: urn:nbn:se:liu:diva-113654DOI: 10.1186/s13148-014-0043-3ISI: 000349045600004PubMedID: 25628767OAI: oai:DiVA.org:liu-113654DiVA: diva2:783815
Available from: 2015-01-27 Created: 2015-01-27 Last updated: 2017-12-05Bibliographically approved

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Guerrero-Bosagna, CarlosJensen, Per

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