liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
Ca2+ transport in isolated mouse liver mitochondria; role of reductive carboxylation and citrate?
Linköping University, Department of Medical and Health Sciences, Cardiology. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Center, Department of Cardiology in Linköping.
1986 (English)In: Cell Calcium, ISSN 0143-4160, E-ISSN 1532-1991, Vol. 7, no 4, 275-282 p.Article in journal (Refereed) Published
Abstract [en]

The uptake of Ca2+ in isolated mouse liver mitochondria respiring on succinate in the presence of rotenone and added Pi, was inhibited by dibucaine, fluorocitrate, p-hydroxymercuribenzoate (PMB), malonate, palmitoyl-CoA, succinyl-CoA and trifluoroperazine. The release of accumulated Ca2+ was stimulated by arsenite, malonate, PMB, palmitoyl-CoA and succinyl-CoA, whereas the release was inhibited by dibucaine, fluorocitrate, trifluoroperazine, and by oligomycin, especially in the presence of ADP. The pyridine nucleotides were oxidized in mitochondria incubated with PMB. The observations suggest a possible contributory role of reductive carboxylation for the uptake of Ca2+, and a possible role of citrate for the retention of Ca2+ in isolated mouse liver mitochondria.

Place, publisher, year, edition, pages
Elsevier, 1986. Vol. 7, no 4, 275-282 p.
National Category
Clinical Medicine
URN: urn:nbn:se:liu:diva-113927DOI: 10.1016/0143-4160(86)90006-0PubMedID: 3768942OAI: diva2:785647
Available from: 2015-02-03 Created: 2015-02-03 Last updated: 2015-02-12

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Alehagen, Urban
By organisation
CardiologyFaculty of Health SciencesDepartment of Cardiology in Linköping
In the same journal
Cell Calcium
Clinical Medicine

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 186 hits
ReferencesLink to record
Permanent link

Direct link