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Initial experiences with serum alkaline DNase activity in monitoring the effects of therapy for carcinoma of the uterine cervix.
Linköping University, Department of Clinical and Experimental Medicine, Division of Clinical Sciences. Linköping University, Faculty of Health Sciences. Department of Obstetrics and Gynecology, Karolinska Hospital, Stockholm, Sweden.
1991 (English)In: European Journal of Cancer, ISSN 0959-8049, E-ISSN 1879-0852, Vol. 27, no 10, 1313-1315 p.Article in journal (Refereed) Published
Abstract [en]

The objective was to evaluate if variations in serum alkaline DNase activity (SADA) can predict the effects of therapy in women with early stages of primary cervical carcinoma. 29 out of 33 patients had no evidence of disease after therapy. Only 5 out of the 29 women showed increased SADA levels after therapy compared with the pretreatment SADA value. Of the 4 women with evidence of disease after therapy, 3 had unchanged or decreased SADA levels. We conclude that serum alkaline DNase activity seems to have little to offer in predicting the effects of treatment in stage I and stage II cervical carcinoma.

Place, publisher, year, edition, pages
1991. Vol. 27, no 10, 1313-1315 p.
National Category
Clinical Medicine
URN: urn:nbn:se:liu:diva-113898PubMedID: 1835604OAI: diva2:785655
Available from: 2015-02-03 Created: 2015-02-03 Last updated: 2015-02-12

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Åvall Lundqvist, Elisabeth
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