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CONTRAIS: CONservative TReatment for Adolescent Idiopathic Scoliosis: a randomised controlled trial protocol
Linköping University, Department of Medical and Health Sciences, Division of Physiotherapy. Linköping University, Faculty of Health Sciences.ORCID iD: 0000-0002-4318-9216
2013 (English)In: BMC Musculoskeletal Disorders, ISSN 1471-2474, Vol. 14, no 1, 261- p.Article in journal (Refereed) Published
Abstract [en]


Idiopathic scoliosis is a three-dimensional structural deformity of the spine that         occurs in children and adolescents. Recent reviews on bracing and exercise treatment         have provided some evidence for effect of these interventions. The purpose of this         study is to improve the evidence base regarding the effectiveness of conservative         treatments for preventing curve progression in idiopathic scoliosis.     


Patients: Previously untreated girls and boys with idiopathic scoliosis, 9 to 17 years of age with at least one year of remaining growth and a curve Cobb angle of 25–40  degrees will be included. A total of 135 participants will be randomly allocated in groups of 45 patients each to receive one of the three interventions.     

Interventions: All three groups will receive a physical activity prescription according to the World Health Organisation recommendations. One group will additionally wear a hyper-corrective night-time brace. One group will additionally perform postural scoliosis-specific exercises.     

Outcome: Participation in the study will last until the curve has progressed, or until         cessation of skeletal growth. Outcome variables will be measured every 6 months. The         primary outcome variable, failure of treatment, is defined as progression of the Cobb         angle more than 6 degrees, compared to the primary x-ray, seen on two consecutive         spinal standing x-rays taken with 6 months interval. Secondary outcome measures include the SRS-22r and EQ5D-Y quality of life questionnaires, the International Physical Activity Questionnaire (IPAQ) short form, and Cobb angle at end of the study.     


This trial will evaluate which of the tested conservative treatment approaches that is the most effective for patients with adolescent idiopathic scoliosis.

Place, publisher, year, edition, pages
2013. Vol. 14, no 1, 261- p.
National Category
Clinical Medicine
URN: urn:nbn:se:liu:diva-114059DOI: 10.1186/1471-2474-14-261OAI: diva2:786618
Available from: 2015-02-05 Created: 2015-02-05 Last updated: 2015-02-17

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Abbott, Allan
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