Comparison between fMRI and Wada test
2004 (English)In: Epilepsia, ISSN 0013-9580, E-ISSN 1528-1167, Vol. 45, no Suppl. 3, 84-84 p.Article in journal, Meeting abstract (Refereed) Published
Purpose: Language lateralisation in patients with epilepsy is more often atypical compared to a normal population. The Wada procedure for testing language and memory has some shortcomings; it is invasive and there is always a risk that the patient becomes too sedated, leading to difficulties in performing the tests. fMR1have shown promising results, showing good correlation to the Wadaprocedure concerning language-lateralisation. The aim of this studywas to investigate if fMRI could be used to determine which hemisphere was language dominant and compare the fMR1 results with the Wada-tests with a focus on patients with a complicated lateralisation.
Method: 4 subjects were tested and they had a heterogeneous (I left handed, I ambidexter and 2 right handed) lateralisation and one had a severe dyslexia. A standard Wada procedure was used and compared with a fMRl investigation using a language paradigm.
Results: The patients studied showed different language lateralisation patterns (2 left hemisphere and 2 bilateral). In two patients the two tests were fully concordant, in the others the fMRI showed a more bilateral pattern.
Conclusion: fMR1 adds valuable information in the pre-surgical investigation for patients with a complex language lateralisation.
Place, publisher, year, edition, pages
Wiley-Blackwell, 2004. Vol. 45, no Suppl. 3, 84-84 p.
Physical Chemistry Chemical Sciences
IdentifiersURN: urn:nbn:se:liu:diva-114151DOI: 10.1111/j.1528-1157.2004.tb04927.xISI: 000222019500285OAI: oai:DiVA.org:liu-114151DiVA: diva2:790564
6th European Congress on Epileptology, Vienna, Austria, May 30th -June 3rd 2004
Times Cited: 0 Borjesson, L Stockhaus, J Gauffin, H Ragnehed, M Lundberg, P Soderfeldt, B 6th European Congress on Epileptology May 30-jun 03, 2004 Vienna, AUSTRIA 0 32015-02-252015-02-112015-03-09Bibliographically approved