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High rate of detection of G8P[6] rotavirus in children with acute gastroenteritis in So Tom, and Principe
University of Nova Lisboa, Portugal.
Linköping University, Department of Clinical and Experimental Medicine, Division of Microbiology and Molecular Medicine. Linköping University, Faculty of Health Sciences.
Linköping University, Department of Clinical and Experimental Medicine, Division of Microbiology and Molecular Medicine. Linköping University, Faculty of Health Sciences.
University of Nova Lisboa, Portugal.
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2015 (English)In: Archives of Virology, ISSN 0304-8608, E-ISSN 1432-8798, Vol. 160, no 2, 423-428 p.Article in journal (Refereed) Published
Abstract [en]

The burden of rotavirus infections greatly affects the low-income African countries. In the absence of epidemiological data on pediatric diarrhea in So Tom, and Principe (STP), a study was conducted from August to December 2011. Rotavirus antigen was detected in 36.7 % of the collected fecal samples (87/237). G8P[6] was identified as the predominant genotype (71.1 % detection rate), while G1P[8] represented only 8.4 %. Phylogenetic analysis of VP7 G8 strains showed clustering within lineage G8d, while VP4 P[6] strains clustered within lineage 1a. Our results represent the first report on rotavirus from STP and show one of the highest detection rates of G8 rotaviruses worldwide.

Place, publisher, year, edition, pages
Springer Verlag (Germany) , 2015. Vol. 160, no 2, 423-428 p.
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:liu:diva-115324DOI: 10.1007/s00705-014-2244-7ISI: 000349433500006PubMedID: 25283609OAI: oai:DiVA.org:liu-115324DiVA: diva2:795078
Note

Funding Agencies|Ministry of Health of STP; Calouste Gulbenkian Foundation (Lisbon, Portugal)

Available from: 2015-03-13 Created: 2015-03-13 Last updated: 2017-12-04

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Sharma, SumitNordgren, Johan

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CiteExportLink to record
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