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Epigenetic modulation of metabolic decisions.
Linköping University, Department of Clinical and Experimental Medicine, Division of Cell Biology. Linköping University, Faculty of Health Sciences.
Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
2015 (English)In: Current Opinion in Cell Biology, ISSN 0955-0674, E-ISSN 1879-0410, Vol. 33, 88-94 p.Article, review/survey (Refereed) Published
Abstract [en]

In the recent years there has been a tremendous increase in our understanding of chromatin, transcription and the importance of metabolites in their regulation. This review highlights what is currently sparse information that suggest existence of a refined system integrating metabolic and chromatin control. We indicate possible regulatory modes, such as feed forward amplification, that may help effect and stabilize long-lasting phenotypic decisions within and even across generations using adipogenesis as the primary context.

Place, publisher, year, edition, pages
2015. Vol. 33, 88-94 p.
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Other Clinical Medicine
URN: urn:nbn:se:liu:diva-115725DOI: 10.1016/ 000352226700014PubMedID: 25588618OAI: diva2:796132
Available from: 2015-03-18 Created: 2015-03-18 Last updated: 2016-05-10

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Öst, Anita
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