Perspectives in Drug Discovery: Central Nervous System Depressants
2014 (English)In: TIAFT Bulletin, ISSN 1103-7660, no 44, 5-16 p.Article in journal (Other academic) Published
This collection of short essays deal with the history of drug discovery and covers a wide range of pharmaceutical substances, including prescription medication as well as illicit recreational drugs of abuse. Consideration was also given to the plethora of drugs encountered in routine forensic casework, especially in traffic crimes, such as driving under the influence of drugs (DUID) and in post-mortem toxicology when drug poisoning deaths are investigated. The essays were written over a number of years and reflect to a large extent my own interests and reading about the history of pharmacology and toxicology of drugs. Background information about the chemistry and pharmacology of many of the most commonly encountered drugs and poisons is presented and this should prove useful in the training of newly recruited staff as well as students starting their studies in pharmacology and toxicology. One aim of the essays was to highlight the human side of pharmacology in medicine by providing details about the scientists who are credited with making the crucial observation when a new therapeutic agent was discovered. Another aim was to highlight the role of serendipity in drug discovery. Abbreviated versions of the essays are scheduled to appear in consecutive issues of the bulletin of The International Association of Forensic Toxicologists (TIAFT).
Place, publisher, year, edition, pages
2014. no 44, 5-16 p.
IdentifiersURN: urn:nbn:se:liu:diva-116709OAI: oai:DiVA.org:liu-116709DiVA: diva2:800077