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Analysis of different methods of assessing the stenotic mitral valve area with emphasis on the pressure gradient half-time concept.
Linköping University, Department of Medicine and Care, Clinical Physiology. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Center, Department of Clinical Physiology in Linköping.
Linköping University, Department of Biomedical Engineering, Physiological Measurements. Linköping University, The Institute of Technology.
Linköping University, Department of Management and Engineering, Applied Thermodynamics and Fluid Mechanics. Linköping University, The Institute of Technology.
1990 (English)In: American Journal of Cardiology, ISSN 0002-9149, E-ISSN 1879-1913, Vol. 66, no 5, 614-620 p.Article in journal (Refereed) Published
Abstract [en]

There are 2 different theoretical models that analyze factors influencing the transmitral pressure gradient half-time (T1/2), defined as the time needed for the pressure gradient to reach half its initial value. In this report the models and the assumptions inherent in them were summarized. One model includes left heart chamber compliance, the other does not. Although the models at a superficial glance seem to be contradictory, the conclusions drawn from them are similar: i.e., T1/2 is influenced not only by valve area, but also by initial maximal pressure gradient and by flow. Different clinical situations in which the T1/2 method for valve area estimation has been shown not to work are analyzed in the 2 models. It is concluded that these models have contributed to our understanding of the T1/2 concept and when it should not be used. We also advocate use of the continuity equation in these situations, since no assumptions then need be made.

Place, publisher, year, edition, pages
1990. Vol. 66, no 5, 614-620 p.
National Category
Fluid Mechanics and Acoustics
URN: urn:nbn:se:liu:diva-116898DOI: 10.1016/0002-9149(90)90490-RPubMedID: 2392981OAI: diva2:801426
Available from: 2015-04-09 Created: 2015-04-09 Last updated: 2015-04-20

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Wranne, BengtAsk, PerLoyd, Dan
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Clinical PhysiologyFaculty of Health SciencesDepartment of Clinical Physiology in LinköpingPhysiological MeasurementsThe Institute of TechnologyApplied Thermodynamics and Fluid Mechanics
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American Journal of Cardiology
Fluid Mechanics and Acoustics

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