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The shape of the proximal isovelocity surface area varies with regurgitant orifice size and distance from orifice: computer simulation and model experiments with color M-mode technique.
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1993 (English)In: Journal of the American Society of Echocardiography, ISSN 0894-7317, E-ISSN 1097-6795, Vol. 6, no 4, 433-445 p.Article in journal (Refereed) Published
Abstract [en]

The hemispheric proximal isovelocity surface area method for quantification of mitral regurgitant flow (i.e., Qc = 2 pi r2v), where 2 pi r2 is the surface area and v is the velocity at radius r, was investigated as distance from the orifice was increased. Computer simulations and steady flow model experiments were performed for orifices of 4, 6, and 8 mm. Flow rates derived from the centerline velocity and hemispheric assumption were compared with true flow rates. Proximal isovelocity surface area shape varied as distance from each orifice was increased and could only be approximated from the hemispheric equation when a certain distance was exceeded: > 7, > 10, and > 12 mm for the 4, 6, and 8 mm orifices, respectively. Prediction of relative error showed that the best radial zone at which to make measurements was 5 to 9, 6 to 14 and 7 to 17 mm for the 4, 6, and 8 mm orifices, respectively. Although effects of a nonhemispheric shape could be compensated for by use of a correction factor, a radius of 8 to 9 mm can be recommended without the use of a correction factor over all orifices studied if a deviation in calculated as compared with true flow of 15% is considered acceptable. These measurements therefore have implications for the technique in clinical practice.

Place, publisher, year, edition, pages
1993. Vol. 6, no 4, 433-445 p.
National Category
Fluid Mechanics and Acoustics
URN: urn:nbn:se:liu:diva-116998PubMedID: 8217210OAI: diva2:801929
Available from: 2015-04-10 Created: 2015-04-10 Last updated: 2015-04-22

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Ask, PerLoyd, DanWranne, Bengt
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Physiological MeasurementsThe Institute of TechnologyApplied Thermodynamics and Fluid MechanicsClinical PhysiologyFaculty of Health SciencesDepartment of Clinical Physiology in Linköping
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Journal of the American Society of Echocardiography
Fluid Mechanics and Acoustics

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