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Recent advances in research on Crimean-Congo hemorrhagic fever
Aristotle University of Thessaloniki, Greece.
Linköping University, Department of Clinical and Experimental Medicine, Division of Microbiology and Molecular Medicine. Linköping University, Faculty of Health Sciences. Swedish Institute Communicable Disease Control, Sweden; National Vet Institute, Sweden.
Karadeniz Technical University, Turkey.
University of Zaragoza, Spain.
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2015 (English)In: Journal of Clinical Virology, ISSN 1386-6532, E-ISSN 1873-5967, Vol. 64, 137-143 p.Article in journal (Refereed) Published
Abstract [en]

Crimean-Congo hemorrhagic fever (CCHF) is an expanding tick-borne hemorrhagic disease with increasing human and animal health impact. Immense knowledge was gained over the past 10 years mainly due to advances in molecular biology, but also driven by an increased global interest in CCHFV as an emerging/re-emerging zoonotic pathogen. In the present article, we discuss the advances in research with focus on CCHF ecology, epidemiology, pathogenesis, diagnostics, prophylaxis and treatment. Despite tremendous achievements, future activities have to concentrate on the development of vaccines and antivirals/therapeutics to combat CCHF. Vector studies need to continue for better public and animal health preparedness and response. We conclude with a roadmap for future research priorities. (C) 2014 Elsevier B.V. All rights reserved.

Place, publisher, year, edition, pages
Elsevier , 2015. Vol. 64, 137-143 p.
Keyword [en]
Crimean-Congo hemorrhagic fever; Ecology; Epidemiology
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:liu:diva-117809DOI: 10.1016/j.jcv.2014.08.029ISI: 000352273600024PubMedID: 25453328OAI: oai:DiVA.org:liu-117809DiVA: diva2:811254
Note

Funding Agencies|European Commission [260427]; Swedish Research Council; NIAID, NIH

Available from: 2015-05-11 Created: 2015-05-08 Last updated: 2015-05-11

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Mirazimi, Ali
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