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A visual grading study for different administered activity levels in bone scintigraphy
Linköping University, Department of Medical and Health Sciences, Division of Radiological Sciences. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center for Surgery, Orthopaedics and Cancer Treatment, Department of Radiation Physics.
Kalmar County Hospital, Sweden.
Örebro University Hospital, Sweden.
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2015 (English)In: Clinical Physiology and Functional Imaging, ISSN 1475-0961, E-ISSN 1475-097X, Vol. 35, no 3, 231-236 p.Article in journal (Refereed) Published
Abstract [en]

IntroductionThe aim of the study is to assess the administered activity levels versus visual-based image quality using visual grading regression (VGR) including an assessment of the newly stated image criteria for whole-body bone scintigraphy. Materials and methodsA total of 90 patients was included and grouped in three levels of administered activity: 400, 500 and 600 MBq. Six clinical image criteria regarding image quality was formulated by experienced nuclear medicine physicians. Visual grading was performed in all images, where three physicians rated the fulfilment of the image criteria on a four-step ordinal scale. The results were analysed using VGR. A count analysis was also made where the total number of counts in both views was registered. ResultsThe administered activity of 600 MBq gives significantly better image quality than 400 MBq in five of six criteria (Pless than005). Comparing the administered activity of 600 MBq to 500 MBq, four criteria of six show significantly better image quality (Pless than005). The administered activity of 500 MBq gives no significantly better image quality than 400 Mbq (Pless than005). The count analysis shows that none of the three levels of administrated activity fulfil the recommendations by the EANM. ConclusionThere was a significant improvement in perceived image quality using an activity level of 600 MBq compared to lower activity levels in whole-body bone scintigraphy for the gamma camera equipment end set-up used in this study. This type of visual-based grading study seems to be a valuable tool and easy to implement in the clinical environment.

Place, publisher, year, edition, pages
Wiley: 12 months , 2015. Vol. 35, no 3, 231-236 p.
Keyword [en]
bone and bones; evaluation; radionuclide imaging; technetium Tc 99 m
National Category
Clinical Medicine
URN: urn:nbn:se:liu:diva-117784DOI: 10.1111/cpf.12155ISI: 000352726400010PubMedID: 24797289OAI: diva2:811286

Funding Agencies|County Council of Ostergotland, Sweden

Available from: 2015-05-11 Created: 2015-05-08 Last updated: 2016-04-11

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Gustafsson, AgnetaOlsson, Anna
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Division of Radiological SciencesFaculty of Medicine and Health SciencesDepartment of Radiation PhysicsCenter for Medical Image Science and Visualization (CMIV)
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