liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
The activity of paraoxonase type 1 (PON-1) in boar seminal plasma and its relationship with sperm quality, functionality, and in vivo fertility
University of Murcia, Spain.
University of Murcia, Spain.
University of Murcia, Spain.
University of Murcia, Spain.
Show others and affiliations
2015 (English)In: Andrology, ISSN 2047-2919, E-ISSN 2047-2927, Vol. 3, no 2, 315-320 p.Article in journal (Refereed) Published
Abstract [en]

Paraoxonase 1 (PON-1) is a hydrolytic enzyme present in body fluids, capable of protecting cells against oxidative stress. The hypothesis was hereby to test that PON-1, present in seminal plasma (SP), acts protecting boar spermatozoa when showing a reasonable high activity in the ejaculate. SP-PON-1 activity differed (pless than0.001) among boars (from 0.10 to 0.29IU/mL). Intra-boar variability was also observed (pless than0.05), but only in two of the 15 boars. SP-PON-1 activity differed among ejaculate portions, showing the spermatozoa-peak portion of spermatozoa-rich ejaculate fraction the highest levels (0.35 +/- 0.03IU/mL, ranging from 0.12 to 0.69) and the post-sperm ejaculate fraction the lowest levels (0.12 +/- 0.01IU/mL, ranging from 0.03 to 0.21). SP-PON-1 activity was positively correlated with the percentage of spermatozoa with rapid and progressive movement (pless than0.01) and negatively correlated with the generation of intracellular reactive oxygen species (pless than0.01) in semen samples after 72h of liquid storage. SP-PON-1 activity was highest (pless than0.01) in boars with highest farrowing rates. In conclusion, SP-PON-1 activity differed among boars and ejaculate fractions/portions. SP-PON-1 activity was positively correlated with sperm quality and functionality of liquid-stored semen samples and it evidenced a positive association with in vivo fertility.

Place, publisher, year, edition, pages
American Society of Andrology , 2015. Vol. 3, no 2, 315-320 p.
Keyword [en]
boar; paraoxonase type 1; semen storage; seminal plasma; sperm functionality; sperm quality
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:liu:diva-118066DOI: 10.1111/andr.309ISI: 000353398800023PubMedID: 25598515OAI: oai:DiVA.org:liu-118066DiVA: diva2:812865
Note

Funding Agencies|MINECO Madrid (Spain) [AGL2012-39903]; FEDER funds (EU); MECD (Madrid, Spain); Seneca Foundation (Murcia, Spain); Science Without Borders Program (Brazilian Scientific Mobility Program at CNPq/MCT)

Available from: 2015-05-20 Created: 2015-05-20 Last updated: 2016-04-25

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Rodriguez-Martinez, Heriberto
By organisation
Division of Clinical SciencesFaculty of Medicine and Health Sciences
In the same journal
Andrology
Clinical Medicine

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 80 hits
ReferencesLink to record
Permanent link

Direct link