The paper potentiostat
2015 (English)In: 4th International Conference on Bio-Sensing Technology, 10-13 May 2015, Lisbon, Portugal., Elsevier, 2015Conference paper, Abstract (Refereed)
This presentation will focus on meeting current challenges in decentralised diagnostics by using amperometric and votammetric systems printed on paper or plastic substrates to deliver inexpensive instruments for a wide range of electroanalytical applications. This approach combines the sophistication of advanced electrochemical biosensors with a simple manufacturing technique to create a use-and-throw instrument. The system is manufactured under ambient conditions. All interconnections are printed and an anisotropic conductive glue is used for interconnection between the chip and conductors. A screen-printed manganese dioxide battery and a vertical electrochromic display are incorporated in the instrument. The display is paper-like in the sense that it works in reflective mode, that is, no backlight is used to light up the pixels. This integrated biosensing platform forms a workhorse in our hands for a variety of diagnostic systems including enzyme electrodes for multi-parametric diabetes monitoring and for the management of chronic kidney disease, electrochemical sensors for enzymes such as G6-P or amylase (a marker for stress), label-free affinity sensors for cancer markers and heart disease, aptasensors for cancer cells, DNA Sensors and robust devices based on imprinted and smart polymers. Using these technologies, we envision over-the-counter paper instruments for self-diagnosis of common diseases such as diabetes, kidney disease and urinary tract infection; inexpensive devices for use by caregivers or paramedics such as the ”Stressometer” or heart attack indicators; home kits to support people after transplant surgery or cancer treatment, smart cartons for pharmaceuticals; pocket tests for allergens, food toxicity, drinking water etc. and strips or patches that communicate with mobile telecommunications. Realisation of these paradigm-changing new products requires the effective harnessing of emerging technology, inspired vision from clinical partners or others “users” and leading-edge engineering to design and produce functional systems in appropriate volumes at the right cost.
Place, publisher, year, edition, pages
IdentifiersURN: urn:nbn:se:liu:diva-118097OAI: oai:DiVA.org:liu-118097DiVA: diva2:813164
4th International Conference on Bio-Sensing Technology, 10-13 May 2015, Lisbon, Portugal.