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The paper potentiostat
Linköping University, Department of Physics, Chemistry and Biology, Biosensors and Bioelectronics. Linköping University, Faculty of Science & Engineering. (Biosensors & Bioelectronics)ORCID iD: 0000-0002-1815-9699
2015 (English)In: 4th International Conference on Bio-Sensing Technology, 10-13 May 2015, Lisbon, Portugal., Elsevier, 2015Conference paper, Abstract (Refereed)
Abstract [en]

This presentation will focus on meeting current challenges in decentralised diagnostics by using amperometric and votammetric systems printed on paper or plastic substrates to deliver inexpensive instruments for a wide range of electroanalytical applications. This approach combines the sophistication of advanced electrochemical biosensors with a simple manufacturing technique to create a use-and-throw instrument. The system is manufactured under ambient conditions. All interconnections are printed and an anisotropic conductive glue is used for interconnection between the chip and conductors. A screen-printed manganese dioxide battery and a vertical electrochromic display are incorporated in the instrument. The display is paper-like in the sense that it works in reflective mode, that is, no backlight is used to light up the pixels. This integrated biosensing platform forms a workhorse in our hands for a variety of diagnostic systems including enzyme electrodes for multi-parametric diabetes monitoring and for the management of chronic kidney disease, electrochemical sensors for enzymes such as G6-P or amylase (a marker for stress), label-free affinity sensors for cancer markers and heart disease, aptasensors for cancer cells, DNA Sensors and robust devices based on imprinted and smart polymers. Using these technologies, we envision over-the-counter paper instruments for self-diagnosis of common diseases such as diabetes, kidney disease and urinary tract infection; inexpensive devices for use by caregivers or paramedics such as the ”Stressometer” or heart attack indicators; home kits to support people after transplant surgery or cancer treatment, smart cartons for pharmaceuticals; pocket tests for allergens, food toxicity, drinking water etc. and strips or patches that communicate with mobile telecommunications. Realisation of these paradigm-changing new products requires the effective harnessing of emerging technology, inspired vision from clinical partners or others “users” and leading-edge engineering to design and produce functional systems in appropriate volumes at the right cost.

Place, publisher, year, edition, pages
Elsevier, 2015.
National Category
Embedded Systems
Identifiers
URN: urn:nbn:se:liu:diva-118097OAI: oai:DiVA.org:liu-118097DiVA: diva2:813164
Conference
4th International Conference on Bio-Sensing Technology, 10-13 May 2015, Lisbon, Portugal.
Available from: 2015-05-21 Created: 2015-05-21 Last updated: 2015-05-28

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Turner, Anthony
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