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Amperometric detection of Francisella tularensis genomic sequence on Zn-mediated diazonium modified substrates
University of Rovira and Virgili, Spain.
University of Rovira and Virgili, Spain.
Linköping University, Department of Physics, Chemistry and Biology, Biosensors and Bioelectronics. Linköping University, Faculty of Science & Engineering.ORCID iD: 0000-0002-1815-9699
Linköping University, Department of Physics, Chemistry and Biology, Biosensors and Bioelectronics. Linköping University, Faculty of Science & Engineering.ORCID iD: 0000-0001-6889-0351
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2015 (English)In: Electrochemistry communications, ISSN 1388-2481, E-ISSN 1873-1902, Vol. 53Article in journal (Refereed) Published
Abstract [en]

A simple, rapid and potentiostat-free method for grafting of close to monolayers of diazonium salts to anchor DNA probes for application in highly sensitive electrochemical genosensing is presented. Zn-mediated grafting is demonstrated to produce a highly organised surface facilitating enhanced sensitivity and a notably reduced detection limit as compared to electrochemical grafting. (C) 2015 Elsevier B.V. All rights reserved.

Place, publisher, year, edition, pages
Elsevier , 2015. Vol. 53
Keyword [en]
Diazonium salt; Surface grafting; Genosensor; Amperometry
National Category
Biological Sciences
Identifiers
URN: urn:nbn:se:liu:diva-118250DOI: 10.1016/j.elecom.2015.02.003ISI: 000353852100002OAI: oai:DiVA.org:liu-118250DiVA: diva2:813534
Note

Funding Agencies|Commission of the European Communities (RTD programme) [2010-SEC-261810]; Generalitat de Catalunya

Available from: 2015-05-22 Created: 2015-05-22 Last updated: 2015-05-22

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Turner, AnthonyBeni, Valerio
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