liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Early response to nanoparticles in the Arabidopsis transcriptome compromises plant defence and root-hair development through salicylic acid signalling
University of Basque Country UPV EHU, Spain.
University of Basque Country UPV EHU, Spain.
Linköping University, Department of Clinical and Experimental Medicine, Division of Cell Biology. Linköping University, Faculty of Health Sciences. University of Basque Country UPV EHU, Spain.ORCID iD: 0000-0002-3894-2218
2015 (English)In: BMC Genomics, ISSN 1471-2164, E-ISSN 1471-2164, Vol. 16, no 341Article in journal (Refereed) Published
Abstract [en]

Background: The impact of nano-scaled materials on photosynthetic organisms needs to be evaluated. Plants represent the largest interface between the environment and biosphere, so understanding how nanoparticles affect them is especially relevant for environmental assessments. Nanotoxicology studies in plants allude to quantum size effects and other properties specific of the nano-stage to explain increased toxicity respect to bulk compounds. However, gene expression profiles after exposure to nanoparticles and other sources of environmental stress have not been compared and the impact on plant defence has not been analysed. Results: Arabidopsis plants were exposed to TiO2-nanoparticles, Ag-nanoparticles, and multi-walled carbon nanotubes as well as different sources of biotic (microbial pathogens) or abiotic (saline, drought, or wounding) stresses. Changes in gene expression profiles and plant phenotypic responses were evaluated. Transcriptome analysis shows similarity of expression patterns for all plants exposed to nanoparticles and a low impact on gene expression compared to other stress inducers. Nanoparticle exposure repressed transcriptional responses to microbial pathogens, resulting in increased bacterial colonization during an experimental infection. Inhibition of root hair development and transcriptional patterns characteristic of phosphate starvation response were also observed. The exogenous addition of salicylic acid prevented some nano-specific transcriptional and phenotypic effects, including the reduction in root hair formation and the colonization of distal leaves by bacteria. Conclusions: This study integrates the effect of nanoparticles on gene expression with plant responses to major sources of environmental stress and paves the way to remediate the impact of these potentially damaging compounds through hormonal priming.

Place, publisher, year, edition, pages
BioMed Central , 2015. Vol. 16, no 341
Keyword [en]
Nanoparticles; Nanotoxycology; Arabidopsis; Defence; Transcriptome; Stress; Systemic acquired response
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:liu:diva-118243DOI: 10.1186/s12864-015-1530-4ISI: 000353764800001PubMedID: 25903678OAI: oai:DiVA.org:liu-118243DiVA: diva2:813541
Note

Funding Agencies|Swedish Research Council-Natural Science (VR-N); Carl Trygger Foundation; VINNOVA-Vinnmer program, Linkoping University; ALF-funding from Ostgota Counties, Sweden; IKERBASQUE-Basque Foundation for Science, Spain

Available from: 2015-05-22 Created: 2015-05-22 Last updated: 2017-12-04

Open Access in DiVA

fulltext(2095 kB)203 downloads
File information
File name FULLTEXT01.pdfFile size 2095 kBChecksum SHA-512
3a089cec570a87fbc79b8145c768817cb4cf8344a40454d833eb5ac121ef91be977e4e63498159c622b4772a69dd61b6886ec52cd2857b2347cb041db407b9cb
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Authority records BETA

Cristobal, Susana

Search in DiVA

By author/editor
Cristobal, Susana
By organisation
Division of Cell BiologyFaculty of Health Sciences
In the same journal
BMC Genomics
Clinical Medicine

Search outside of DiVA

GoogleGoogle Scholar
Total: 203 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 106 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf