Capacitive biosensor for detection of toxicity biomarkers
2015 (English)Manuscript (preprint) (Other academic)
Microfluidic devices are rapidly gaining importance for in vitro toxicity testing. Biomarker detection in microfluidic assays are however challenging due to small sample sizes and low analyte concentration. Capacitive electrochemical biosensors have been reported to have high sensitivity and properties that are amenable for implementation into microfluidic devices.
In this work a biosensor application for troponin T (TnT) is presented. The sensor showed linear response to analyte over five orders of magnitude with the lowest detectable signal at 10-13 M. The sensor proved to be able to detect TnT spiked in cell culture media at concentrations relevant for cell cultures.
Place, publisher, year, edition, pages
Biological Sciences Physical Sciences
IdentifiersURN: urn:nbn:se:liu:diva-118293OAI: oai:DiVA.org:liu-118293DiVA: diva2:814064