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Height, weight and body mass index in adults with congenital heart disease
Umeå University, Sweden; Umeå University, Sweden; Umeå University, Sweden.
Umeå University, Sweden; Umeå University, Sweden.
University of Gothenburg, Sweden.
Lund University, Sweden.
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2015 (English)In: International Journal of Cardiology, ISSN 0167-5273, E-ISSN 1874-1754, Vol. 187, 219-226 p.Article in journal (Refereed) Published
Abstract [en]

Background: High BMI is a risk factor for cardiovascular disease and, in contrast, low BMI is associated with worse prognosis in heart failure. The knowledge on BMI and the distribution in different BMI-classes in adults with congenital heart disease (CHD) are limited. Methods and results: Data on 2424 adult patients was extracted from the Swedish Registry on Congenital Heart Disease and compared to a reference population (n = 4605). The prevalence of overweight/obesity (BMI greater than= 25) was lower in men with variants of the Fontan procedure, pulmonary atresia (PA)/double outlet right ventricle (DORV) and aortic valve disease (AVD) (Fontan 22.0% and PA/DORV 15.1% vs. 43.0%, p = 0.048 and p less than 0.001) (AVD 37.5% vs. 49.3%, p less than 0.001). Overt obesity (BMI greater than= 30) was only more common in women with AVD (12.8% vs. 9.0%, p = 0.005). Underweight (BMI less than 18.5) was generally more common in men with CHD (complex lesions 4.9% vs. 0.9%, p less than 0.001 and simple lesions 3.2% vs. 0.6%, less than0.001). Men with complex lesions were shorter than controls in contrast to females that in general did not differ from controls. Conclusion: Higher prevalence of underweight in men with CHD combined with a lower prevalence of over-weight/obesity in men with some complex lesions indicates that men with CHD in general has lower BMI compared to controls. In women, only limited differences between those with CHD and the controls were found. The complexity of the CHD had larger impact on height in men. The cause of these gender differences as well as possible significance for prognosis is unknown. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

Place, publisher, year, edition, pages
Elsevier , 2015. Vol. 187, 219-226 p.
Keyword [en]
Congenital heart disease; Body mass index; Height; Weight; Adult
National Category
Public Health, Global Health, Social Medicine and Epidemiology
URN: urn:nbn:se:liu:diva-119591DOI: 10.1016/j.ijcard.2015.03.153ISI: 000354905600063PubMedID: 25838217OAI: diva2:825124

Funding Agencies|Swedish Heart-Lung Foundation [20100355, 20130472]; Heart Foundation of Northern Sweden; research foundation of The Swedish Heart and Lung Association [E116/12, E115/13]; research foundation of Healthcare Professions within Cardiology; Umea University and Vasterbottens lans landsting (the County of Vasterbotten) [316351]

Available from: 2015-06-23 Created: 2015-06-22 Last updated: 2015-07-08

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Nielsen, Niels Erik
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Division of Cardiovascular MedicineFaculty of Health SciencesDepartment of Cardiology in Linköping
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International Journal of Cardiology
Public Health, Global Health, Social Medicine and Epidemiology

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