liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
Posterior Cingulate Cortex Integrates the Senses of Self-Location and Body Ownership
Karolinska Institute, Sweden.
Linköping University, Department of Clinical and Experimental Medicine, Division of Neuro and Inflammation Science. Linköping University, Faculty of Medicine and Health Sciences. Karolinska Institute, Sweden.
Karolinska Institute, Sweden.
Karolinska Institute, Sweden.
2015 (English)In: Current Biology, ISSN 0960-9822, E-ISSN 1879-0445, Vol. 25, no 11, 1416-1425 p.Article in journal (Refereed) Published
Abstract [en]

The senses of owning a body and being localized somewhere in space are two key components of human self-consciousness. Despite a wealth of neurophysiological and neuroimaging research on the representations of the spatial environment in the parietal and medial temporal cortices, the relationship between body ownership and self-location remains unexplored. To investigate this relationship, we used a multisensory out-of-body illusion to manipulate healthy participants perceived self-location, head direction, and sense of body ownership during high-resolution fMRI. Activity patterns in the hippocampus and the posterior cingulate, retrosplenial, and intraparietal cortices reflected the sense of self-location, whereas the sense of body ownership was associated with premotor-intraparietal activity. The functional interplay between these two sets of areas was mediated by the posterior cingulate cortex. These results extend our understanding of the role of the posterior parietal and medial temporal cortices in spatial cognition by demonstrating that these areas not only are important for ecological behaviors, such as navigation and perspective taking, but also support the perceptual representation of the bodily self in space. Our results further suggest that the posterior cingulate cortex has a key role in integrating the neural representations of self-location and body ownership.

Place, publisher, year, edition, pages
Elsevier (Cell Press) , 2015. Vol. 25, no 11, 1416-1425 p.
National Category
Neurology
Identifiers
URN: urn:nbn:se:liu:diva-119794DOI: 10.1016/j.cub.2015.03.059ISI: 000355556600016PubMedID: 25936550OAI: oai:DiVA.org:liu-119794DiVA: diva2:827258
Note

Funding Agencies|Swedish Research Council; James McDonnell Foundation; Soderbergska Stiftelsen; European Research Council; European Union [PIOF-GA-2012-302896]

Available from: 2015-06-26 Created: 2015-06-26 Last updated: 2015-06-26

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Björnsdotter Åberg, Malin
By organisation
Division of Neuro and Inflammation ScienceFaculty of Medicine and Health Sciences
In the same journal
Current Biology
Neurology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 243 hits
ReferencesLink to record
Permanent link

Direct link