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Does the changing sex ratio of multiple sclerosis give opportunities for intervention?
Linköping University, Department of Clinical and Experimental Medicine, Division of Neuro and Inflammation Science. Region Östergötland, Local Health Care Services in Central Östergötland, Department of Neurology. Linköping University, Faculty of Health Sciences.
Linköping University, Department of Clinical and Experimental Medicine, Division of Neuro and Inflammation Science. Linköping University, Faculty of Health Sciences. Region Östergötland, Local Health Care Services in Central Östergötland, Department of Neurology. Uppsala University, Sweden.
2015 (English)In: Acta Neurologica Scandinavica, ISSN 0001-6314, E-ISSN 1600-0404, Vol. 132, 42-45 p.Article, review/survey (Refereed) Published
Abstract [en]

In several international studies, an increasing women-to-men (w/m) ratio in patients with multiple sclerosis (MS) has been reported. Such sex ratios have been analysed by year of onset or by year of birth. In a Swedish study, data from the Swedish MS register (SMSreg) were used to analyse the w/m ratio in Sweden. The sex ratio was analysed both by year of birth (8834 patients) and by year of onset (9098 patients). No increased w/m ratio was seen in this study. The age-specific sex ratio did not demonstrate any significant changes. However, a new investigation of the sex ratio in Sweden, based on data from all available data sources (19,510 patients), showed a significantly increased w/m ratio of MS in Sweden from 1.70 to 2.67. Environmental factors such as cigarette smoking, hormonal factors and nutrition are of interest in this context, but the cause of the increasing w/m ratio in MS is yet not possible to explain.

Place, publisher, year, edition, pages
Wiley , 2015. Vol. 132, 42-45 p.
Keyword [en]
environmental; multiple sclerosis; sex ratio
National Category
Neurology
Identifiers
URN: urn:nbn:se:liu:diva-119782DOI: 10.1111/ane.12430ISI: 000355852600008PubMedID: 26046558OAI: oai:DiVA.org:liu-119782DiVA: diva2:827290
Available from: 2015-06-26 Created: 2015-06-26 Last updated: 2015-07-07

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Boström, IngerLandtblom, Anne-Marie
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Division of Neuro and Inflammation ScienceDepartment of NeurologyFaculty of Health Sciences
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Acta Neurologica Scandinavica
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