The optimal number of offspring per gamete donor
2015 (English)In: Acta Obstetricia et Gynecologica Scandinavica, ISSN 0001-6349, E-ISSN 1600-0412, Vol. 94, no 9, 1022-1026 p.Article in journal (Refereed) Published
Our aim was to create a mathematical basis to calculate the risks for unintended matings of consanguineous half-siblings from a donor in a society with approximately 10 million inhabitants. The Curie-Cohen model for calculation of the risk for consanguineous mating was used. When the number of offspring per donor is limited to 10, then the model gives a yearly risk for consanguineous matings below 1%. Thus 10 offspring gives a risk for consanguineous matings of 0.9% per year, or approximately once in every 100years. The risk increases exponentially: with 15 offspring it exceeds 2% and with 25 it reaches up above 5%.
Place, publisher, year, edition, pages
Informa Healthcare / Wiley , 2015. Vol. 94, no 9, 1022-1026 p.
Number of children; donor; mathematical model; consanguinity; fertility
Clinical Medicine Mathematics
IdentifiersURN: urn:nbn:se:liu:diva-120855DOI: 10.1111/aogs.12678ISI: 000359086600017PubMedID: 26014908OAI: oai:DiVA.org:liu-120855DiVA: diva2:849473
Funding Agencies|National Tissue Group for Gametes (VOG Konsceller) at the National Council for Human Organs and Tissues (Nationella Vavnadsradet) at the Swedish Association of Local Authorities and Regions (SALAR)2015-08-282015-08-282016-06-08